I have to admit that I'm not the optimal reviewer for this product. After reading the premise, and having really enjoyed the author's other works, I swooped right in and grabbed this.
The issue, for me, is that this is much more of a mechanical rulebook than it is a setting book. It's kind of a shame, because you can catch fleeting glimpses of a rich and exciting post-apocalyptic setting -- not an easy feat when in such well-trod territory!
The book does lay out several example encounters, and it's possible that this is all intended as Mind Fertilizer, so that any GM can truly make the game their own. There's certainly nothing wrong with that, but I can't help but get the feeling that Matt Davids has already done a lot of work to make a vibrant, living, radioactive world behind his screen, and I'd love to take a look.
The product is truly put together very well. The layout and graphics are pretty slick, the rules do look like they'd make for some nail-biting gameplay, and there are random tables galore. If that's something you're looking for, you'll be satisfied! In the meantime, I'll hope that DiceGeeks release a campaign sourcebook that details the history and flavor of the setting.